Protect…Detect…Prevent!

Prepared for the Scientific Guidance Panel Biomonitoring California November 8, 2021

Metallosis is a potentially fatal complication seen in metal on metal hip replacements caused by erosion and release of metallic debris triggering a massive discharge of cytokines from inflammatory cells. The systemic absorption of metal ions like cobalt and chromium can cause a spectrum of clinical diseases.[https://www.ejropen.com/article/S2352–0477%2814%2900011–2/fulltext]
EPA Map of Particulate Emissions in tons per year shows >20 (red) in the India Basin north entry to the federal Superfund site adjacent to the Hunters Point hilltop where she has owned a home for over 20 years.
The Evans street route to the federal Superfund site traveling southeast toward the Innes street north gate is a region exceeding the 100th percentile in PM 2.5 detections according to the EPA EJSCREEN map. The patient’s son uses a home particulate monitor.
Innes Avenue north entry federal Superfund site Hunters Point Shipyard
Urinary toxic exposure screening detects elevations in gadolinium, cobalt and high normal levels of chromium. Global nutrient deficiencies are evident in this physically impaired senior whose hip and back pain interferes with her ability to prepare meals and climb stairs in her home. Gadolinium is used in contrast agents to visualize soft tissues. It is also used for neutron shielding in nuclear submarines and occurs naturally in the serpentinite bedrock of the Hunters Point hilltop.
https://www.drugwatch.com/hip-replacement/metallosis/
Metal on Metal (MoM) hip replacements were sold in the US from 2002 to 2014. None of the models received FDA approval and none were subjected to clinical trials. [https://westernjusticelaw.com/metal-on-metal-hip-replacements]
Extensive fibrosis and metallosis in a prosthetic knee. Metal particles deposit in tissue causing necrosis and excite an inflammatory response when cobalt, chromium and stainless steel are used in joint prosthesis. {https://ispub.com/IJPA/4/2/10194]
Radiological features of osteoarthritis, metallosis and aseptic loosening of the right hip. [https://www.researchgate.net/figure/Radiological-and-macroscropic-tissue-features-of-OA-AL-and-metallosis-a-Anteroposterior_fig6_304998344]
Dr. Dahlgren can be contacted at dahlgren@envirotoxicology.com
https://www.sfexaminer.com/features/doing-no-harm-ahimsa-sumchai/

Ahimsa Porter Sumchai MD, PD - Medical Director & PI. Founding Chair- Radiological Committee Hunters Point Shipyard RAB Attending MD VA Toxic Registry and SFDPH